Female geriatric patients with traumatic brain injury have better odds of survival compared to men-a meta-analysis and review of the literature

Authors

  • Shreya Pandya Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Ivan Fedoriv Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Timothy N. Le Department of Surgery, Staten Island University, Staten Island, New York, New York, USA http://orcid.org/0000-0002-9132-8794
  • Jacqueline Liu City University of New York (CUNY) School of Medicine, New York, New York, USA
  • Tori Singer Touro College of Osteopathic Medicine, New York, New York, USA
  • Kaitlyn Kennedy City University of New York (CUNY) School of Medicine, New York, New York, USA
  • Kiara Singer Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Bryan Lee Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Vincent Kaykaty Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Kevin Butler Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Kailey Singh Touro College of Osteopathic Medicine, New York, New York, USA
  • Nikhil Patel Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Frank DiRoma Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Asaf Gave Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Ronit Gilad Department of Surgery, Staten Island University, Staten Island, New York, New York, USA
  • Duraid Younan Department of Surgery, Staten Island University, Staten Island, New York, New York, USA

DOI:

https://doi.org/10.18203/2349-2902.isj20221722

Keywords:

Trauma, Geriatric, Female, Gender, TBI

Abstract

Geriatric trauma patients have worse outcomes compared to younger patients. Differences in trauma outcomes based on gender remain unproven. We sought to investigate the association of gender with outcomes among geriatric patients with traumatic brain injury (TBI) by performing a meta-analysis and review of the literature. A systematic review of published articles on outcomes of geriatric patients with TBI using PubMed was conducted. A total of 363 articles were identified, from these, 74 articles met the inclusion criteria of isolated TBI in geriatric patients. Upon review of the articles, only 5 met the specified criteria of the search which described male and female mortality amongst geriatric patients suffering isolated TBI. The data from these papers were combined into a master file and meta-analysis was performed using random-effect model with Rev Man 5.4 software. The total number of patients in these 5 papers was 23,893, of these 11,971 were men and 11,922 were women. The odds ratio for survival in these patients were 1.40, 2.40, 1.20, 1.28 and 1.15 with a combined final OR of 1.28 favoring women with a p value of less than 0.00001 and CI of 1.21-1.36. Female geriatric trauma patients sustaining TBI have better survival than men.

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Published

2022-06-27

Issue

Section

Meta-Analysis