DOI: http://dx.doi.org/10.18203/2349-2902.isj20210984

Recurrent leiomyosarcoma with de-differentiation to chondrosarcoma and osteosarcoma: a case report

Zara Summers, Aemelia Melloy, Eshwarshanker Jeyarajan, Timothy Wills, David Parker, Leigh Rutherford, Philip Townend

Abstract


Leiomyosarcoma are a rare type of tumour of smooth muscle that can be found in the retroperitoneum. There is a paucity of reported data around dedifferentiation of leiomyosarcoma. Our case report describes de-differentiation of recurrent leiomyosarcoma into osteosarcoma and chondrosarcoma in a patient who had a local recurrence of his leiomyosarcoma. The recurrence is on a background of intermediate grade leiomyosarcoma of the retroperitoneum and he underwent his original resection in 2019 and included a right nephrectomy and right hemicolectomy. Our patient is currently undergoing radiotherapy and we will continue ongoing follow up for his progress.


Keywords


Leiomyosarcoma, Retroperitoneum, Chondrosarcoma, Osteosarcoma

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References


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