An ulcerated exophytic tumour over the gluteal area- eccrine porocarcinoma in an immunocompetent female

Authors

  • Ashok Kumar Department of General Surgery, Lady Hardinge Medical College, New Delhi, India
  • Spandana Jagannath Department of General Surgery, Lady Hardinge Medical College, New Delhi, India
  • Ravi H. Phulware Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India
  • Vibhu Mendiratta Department of Dermatology, Lady Hardinge Medical College, New Delhi, India

DOI:

https://doi.org/10.18203/2349-2902.isj20211837

Keywords:

Porocarcinoma, Appendageal tumour, Eccrine sweat gland tumour

Abstract

Porocarcinoma is a very rare type of skin cancer arising from the eccrine sweat glands and is poorly understood. The exact pathogenesis is unknown. Clinical features are non-specific. It may present as a painless, slow growing mass or nodule, ulcer, plaque, swelling, wart, papule or naevus that increases in size over years to decades and may ulcerate or bleed upon trauma. They occur equally in both sexes and are most commonly found in the lower extremity. Though metastasis is rare, they are considered aggressive with high mortality rate. Diagnosis requires standard histopathological studies. Immunohistochemistry is useful in difficult cases. Treated early, eccrine porocarcinoma is curable by wide excision. The author reports the case of an eccrine porocarcinoma in the lower extremity of an elderly lady and a summary of its clinical, radiological and histological findings is illustrated.

References

Robson A, Greene J, Ansari N, Kim B, Seed PT, McKee PH, Calonje E. Eccrine porocarcinoma (malignant eccrine poroma): a clinicopathologic study of 69 cases. Am J Surg Pathol. 2001;25(6):710-20.

Mishima Y, Morioka S. Oncogenic differentiation of the intraepidermal eccrine sweat duct: eccrine poroma, poroepithelioma and porocarcinoma, Dermatology. 1969;138(4):238-50.

Akalin T, Sen S, Yuceturk A, Kandiloglu G. P53 protein expression in eccrine poroma ans porocarcinoma, Am J Dermatopathol. 2001;23(5):402-6.

Salih AM, Kakamad FH, Baba HO. Porocarcinoma; presentation and management, a meta-analysis of 453 cases. Ann Med Surg (Lond). 2017;20:74-9.

Mahomed F, Blok J, Grayson W. The squamous variant of eccrine porocarcinoma: a clinicopathological study of 21 cases. J Clin Pathol. 2008;61(3):361-5.

Tidwell WJ, Mayer JE, Malone J, Schadt C, Brown T. Treatment of eccrine porocarcinoma with Mohs micrographic surgery: a cases series and literature review. Int J Dermatol. 2015;54(9):1078-83.

Downloads

Published

2021-04-28

Issue

Section

Case Reports