Comparative study in healing process and complications inpatient undergoing ventral hernia mesh repair with and without the usage of collagen granules

A. P. Subburaaj, Sahaya Rani Joycey, Preethiya S., Arun Balaji, Nabeel Yusaf


Background: Ventral hernias are the second most common type of hernias accounting for 21 to 35% of all types of hernias. Collagen is defined as an endogenous substance that forms an important structural component in connective tissue. Collagen granules have an advantage with a reduction in inflammatory cells during healing resulting in decreased days of healing. This study is to compare the outcome of a patient with and without collagen granules usage during ventral hernia open mesh repair.

Methods: This prospective comparative study was done in 50 cases of ventral hernias admitted to the department of surgery in VMKV Medical College, Salem between periods of March 2018 to October 2019 were chosen for the study. The test group was treated with collagen granules and the control group was collagen granules not been used during ventral hernia mesh repair.

Results: Most common surgical approach used in ventral hernia is open mesh repair. The study shows a group of patients where collagen granules are used after mesh fixation has faster wound healing, reduced seroma, and hematoma collection, and reduced hospital stay, reduced infection compared to the group of patients who undergone non-collagen closure.  

Conclusions: The study shows a group of patients where collagen granules are used after mesh fixation has faster wound healing, reduced seroma, and hematoma collection, and reduced hospital stay, reduced infection compared to the group of patients who underwent non-collagen closure.


Epigastric hernia, Hypertension, Incisional hernia, Surgical site infection

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