DOI: http://dx.doi.org/10.18203/2349-2902.isj20205874

Space occupying lesions of liver- clinical presentation, investigations and management: a longitudinal study

Rajiv Sonarkar, Giriraj Gajendra, T. R. V. Wilkinson, Shreyas Sonawane

Abstract


Background: Liver is a common site for space occupying lesions. The objective of this study was to determine the aetiologies of space occupying lesion of liver and their clinical presentation and correlate imaging; to evaluate the treatment modalities of space occupying lesion of liver and their outcome.

Methods: A 2-year tertiary care teaching hospital based longitudinal study with 63 patients was done. Selection criteria was defined and a prestructured proforma was made to assess and note the findings.

Results: The mean age of occurrence of space occupying lesions of liver was 47.19±14.53 years. Space occupying lesions of liver was commonly observed in 5th decade of life. Males were affected more than females. Metastatic lesion of liver were the most common cause of liver SOL (34.9%) followed by liver abscesses.

Conclusions: Majority of space occupying lesions are metastatic lesion followed by liver abscesses. Majority of space occupying lesions were surgically managed.


Keywords


Benign liver lesions, Liver abscess, Liver imaging, Malignant liver lesions, Space occupying lesion

Full Text:

PDF

References


Jarnagin WR, ed. Blumgart’s Surgery of the Liver, Biliary Tract and Pancreas. 5th edn. Elsevier Saunders; 2013.

Bryan PJ, Dinn WM, Grossman ZD, Wistow BW, McAfee JG, Kieffer SA. Correlation of computed tomography, grey scale ultrasonography, and radionuclide imaging of the liver in detecting space occupying processes. Radiology. 1977;124(2):387-93.

Feldman M, Friedman LS, Brandt LJ. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease Pathophysiology, Diagnosis, Management. 10th edn. Elsevier Saunders; 2016:24.

Kaltenbach TEM, Engler P, Kratzer W, Oeztuerk S, Seufferlein T, Haenle MM, et al. Prevalence of benign focal liver lesions: ultrasound investigation of 45,319 hospital patients. Abdom Radiol. 2016;41(1):25-32.

Abou-Shady M, Zakaria H, Alwaraky M. Nonparasitic liver cysts: different treatment strategies. Egypt J Surg. 2016;35(4):438.

Dardik H. Solitary hepatic cysts. J Am Coll Surg. 2001;192(6):804.

Akther J, Khanam N. Clinico epidemiological profile of hydatid diseases in central india, a retrospective & prospective study. Int J Biol Med Res. 2011;2(3):603-6.

Palanivelu C, Jani K, Malladi V, Senthilkumar R, Rajan PS, Sendhilkumar K, et al. Laparoscopic management of hepatic hydatid disease. J Soc Laparosc Surg. 2006;10(1):56-62.

Ezer A, Nursal TZ, Moray G, Yildirim S, Karakayali F, Noyan T, et al. Surgical treatment of liver hydatid cysts. HPB. 2006;8(1):38-42.

Jayakar SR, Nichkaode PB. Liver abscess, management strategies, and outcome. Int Surg J. 2018;5(9):3093.

Christopher S, Kumar A, Achar S. Liver abscess-various modalities of treatment and its clinical outcome. Int Surg J. 2016;3(4):1868–74.

Sheefa H, Lata J, Basharat M, Rumana M, Veena M. Utility of FNAC in conjunction with cell block for diagnosing space-occupying lesion (SOL) of liver with emphasis on differentiating hepatocellular carcinoma from metastatic SOL: Analysis of 61 cases. Oman Med J. 2016;31(2):135-41.

Edris AMM, Ali IM, Bakeit SB, Abashar M, Siddig EE. Diagnostic importance of ultrasound-guided fine needle aspiration in diagnosing hepatic lesions among sudanese patients 2015. Asian Pacific J Cancer Prev. 2016;17(2):553-5.

Hima BP, Shukla AK, Krishnappa N. Sonographic evaluation of focal and diffuse hepatic lesions. J Evol Med Dent Sci. 2014;3(45):11114-30.

Thimmaiah VT. Evaluation of focal liver lesions by ultrasound as a prime imaging modality. Sch J App Med Sci Ed. 2013;1(6):1041-59.

Patel S, Nichkaode PB, Bansod PY, Akhtar M. Imaging and cytopathological correlation of space occupying lesions in liver: a prospective observational study. Int Surg J. 2017;4(5):1687-96.

Mallick SI, bhusan Sarkar P, Dasgupta S, Kar A, Mukherjee S, Bothra SJ, et al. Evaluation of liver space occupying lesion with special reference to etiology and co-morbid condition. Int J Curr Res Rev. 2015;7(1):28-33.

Dietrich CF, Kratzer W, Strobel D, Danse E, Fessl R, Bunk A, et al. Assessment of metastatic liver disease in patients with primary extrahepatic tumors by contrast-enhanced sonography versus CT and MRI. World J Gastroenterol. 2006;12(11):1699.

Singh S, Chaudhary P, Saxena N, Khandelwal S, Poddar DD, Biswal UC. Treatment of liver abscess: Prospective randomized comparison of catheter drainage and needle aspiration. Ann Gastroenterol. 2013;26(4):332-9.