Role of carbon dioxide laser in the treatment of oral leukoplakia

Pankaj Kshirsagar, Prabhat B. Nichkaode, Dipti A. Patil, Balajiprathep Santhan


The aim of the present study is to evaluate the treatment results of carbon dioxide (CO2) laser vaporisation in the well-defined cohort patients with oral leukoplakia. The group consisted of 20 patients. Before treatment, a clinical photograph and an incisional biopsy were performed in all the cases. Also, post treatment results were documented with clinical photographs. The mean follow-up period was 12 months. 18 out of 20 patients treated for cure (90%) achieved local control after one treatment. The remaining 2 patients required (10%) 2nd and 3rd vaporisations. The rate of malignant transformation after CO2 laser treatment is found to be 2.27% which is comparable to the other studies. CO2 laser vaporisation in the treatment of oral leukoplakia lesions is an excellent procedure in not only preventing the local recurrence and the malignant transformation but also in preventing the post-operative dysfunction. It is a time saving procedure with a negligible intra operative bleeding. The wound healing procedure after CO2 laser is extremely good causing the least post procedure morbidity.


Oral leukoplakia, CO2 laser vaporisation, Malignant transformation

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