A case of adrenal cortical carcinoma with inferior vena cava thrombus extending into the right atrium: a two staged procedure

Authors

  • Chandranathan Magesh Department of Genitourinary Surgery, Apollo Main Hospital, Chennai, Tamil Nadu
  • Mathisekaran Thangarasu Department of Genitourinary Surgery, Apollo Main Hospital, Chennai, Tamil Nadu
  • SanjayPrakash JayaPrakash Department of Genitourinary Surgery, Apollo Main Hospital, Chennai, Tamil Nadu
  • Nitesh Jain Department of Genitourinary Surgery, Apollo Main Hospital, Chennai, Tamil Nadu

DOI:

https://doi.org/10.18203/2349-2902.isj20204160

Keywords:

Adrenal cortical carcinoma, Atrial clot evacuation, Inferior venacava thrombectomy, Nephroadrenalectomy

Abstract

We present a case of adrenal cortical carcinoma (ACC) with tumor thrombus involving the inferior vena cava (IVC) and right atrium in a morbidly obese, middle-aged female. ACC is a rare type of cancer with a poor outcome. Most cases present with metastasis at the time of initial presentation. This patient presented with breathing difficulty and flank pain. With endocrinology evaluation and collaborative effort of multidisciplinary teams, the patient successfully underwent staged procedures of atrial clot evacuation after thoracotomy with cardiopulmonary bypass (CBP) along with inferior vena cava thrombectomy (IVCT) and left radical nephroadrenalectomy. The two staged procedure reduces the mortality when compared with a single staged procedure. The patient underwent atrial clot evacuation, performed by cardiothoracic surgery team under CBP and deployment of IVC filter by interventional radiologist as a first staged procedure. At six months of follow-up, the patient had locoregional disease spread but with good functional status. This case report highlights that even a high-volume disease, with proper planning by an experienced surgical team, can be operated successfully with an acceptable post-surgery quality of life for the patients.

Author Biography

Mathisekaran Thangarasu, Department of Genitourinary Surgery, Apollo Main Hospital, Chennai, Tamil Nadu

REGISTRAR 

APOLLO MAIN HOSPITAL, CHENNAI

References

Fassnacht M, Terzolo M, Allolio B, Baudin E, Haak H, Berruti A, et al. Combination chemotherapy in advanced adrenocortical carcinoma. N Engl J Med. 2012;366(23):2189-97.

Langenhuijsen J, Birtle A, Klatte T, Porpiglia F, Timsit MO. Surgical management of adrenocortical carcinoma: Impact of Laparoscopic Approach, Lymphadenectomy, and Surgical Volume on Outcomes- A Systematic Review and Meta-analysis of the Current Literature. Euro. Urol Focus. 2016;1(3):241-50.

Zini L, Porpiglia F, Fassnacht M. Contemporary management of adrenocortical carcinoma. Euro Uro. 2011;60(5):1055-65.

Mayr R, Pycha A, Burger M. The perioperative management of metabolically active tumors. Euro Uro Focus. 2016;1(3):258–60.

Reibetanz J, Jurowich C, Erdogan I, Nies C, Rayes N, Dralle H, et al. Impact of lymphadenectomy on the oncologic outcome of patients with adreno-cortical carcinoma. Ann Surg. 2012;255(2):363-9.

Polat B, Fassnacht M, Pfreundner L, Guckenberger M, Bratengeier K, Johanssen S, et al. Radiotherapy in adrenocortical carcinoma. Canc. 2009;115(13):2816-23.

Nomine-Criqui C, Germain A, Ayav A, Bresler L, Brunaud L. Robot-assisted adrenalectomy: indi-cations and drawbacks. Upd Surg. 2017;69(2):127-33.

Downloads

Published

2020-09-23

Issue

Section

Case Reports