DOI: http://dx.doi.org/10.18203/2349-2902.isj20201899

Gastric Schwannoma mimicking gastrointestinal stromal tumor: a rare case with review of literature

Nagari Bheerappa, Digvijoy Sharma, Gangadhar Rao Gondu, Nirjhar Raj, Kamal Kishore Bishnoi, Venu Madhav Thumma, Suryaramachandra Varma Gunturi

Abstract


Gastric schwannoma (GS) is a rare neoplasm of the stomach. It accounts for 0.2% of all gastric tumors and is mostly benign, slow-growing, and asymptomatic. Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors and up to 60-70% of GIST occur in the stomach. Schwannoma and GIST have similar radiological and endoscopic features making it extremely difficult to differentiate them preoperatively. Differential diagnosis of these two submucosal tumors is important because of the malignant potential of GIST and the relatively benign course of gastric schwannomas. This case stresses on the importance of including gastric schwannomas in the differential diagnosis of a submucosal gastric mass as it has the ability to mimic a gastrointestinal stromal tumor, which is a leading differential diagnosis because of its common occurrence at this site.


Keywords


Gastric schwannoma, GIST, Resection

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References


Sreevathsa MR, Pipara G. Gastric schwannoma: a case report and review of literature. J Surg Oncol. 2015;6:123-6.

Daimaru Y, Kido H, Hashimoto H, Enjoji M. Benign schwannoma of the gastrointestinal tract: a clinicopathologic and immunohistochemical study. Hum Pathol. 1988;19:257-64.

Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol. 2002;33:459-65.

Prévot S, Bienvenu L, Vaillant JC, de Saint-Maur PP. Benign schwannoma of the digestive tract: a clinicopathologic and immunohistochemical study of five cases, including a case of esophageal tumor. Am J Surg Pathol. 1999;23:431-6.

Yoon W, Paulson K, Mazzara P, Nagori S, Barawi M, Berri R. Gastric schwannoma: a rare but important differential diagnosis of a gastric submucosal mass. Case Rep Surg. 2012;2012:280982.

Melvin WS, Wilkinson MG. Gastric schwannoma. Clinical and pathologic considerations. Am Surg. 1993;59:293-6.

Miettinen M. Gastrointestinal stromal tumors. An immunohistochemical study of cellular differentiation. Am J Clin Pathol. 1988;89:601-10.

Sakai F, Sone S, Yanagisawa S, Ishii Z. Schwannoma of lesser omentum. Eur J Radiol. 1988;8:113-4.

Muhammad A. An unusual case of gastric schwannoma. J Coll Phys Surg Pak. 1997;7:80-1.

Atmatzidis S, Chatzimavroudis G, Dragoumis D, Tsiaousis P, Patsas A, Atmatzidis K. Gastric schwannoma: a case report and literature review. Hippokratia. 2012;16:280-2.

Kan YK, Kang HJ, Kim KM, Sohn T, Choi D, Ryu MH et al. Clinical practice guideline for accurate diagnosis and effective treatment of gastrointestinal stromal tumor in Korea. Cancer Res Treat. 2012;44:85-96.

Hong X, Wu W, Wang M, Liao Q, Zhao Y. Benign gastric schwannoma: how long should we follow up to monitor the recurrence? A case report and comprehensive review of literature of 137 cases. Internat Surg. 2015;100:744-7.