Role of hyperoxygenation on surgical site wound infection: a randomised case control study

Authors

  • Samba Siva Rao G. Department of General Surgery, 2Mamata Medical College, Khammam, Telangana, India
  • Kiran Kumar Suggala Department of Anaesthesia, Mamata Medical College, Khammam, Telangana, India

DOI:

https://doi.org/10.18203/2349-2902.isj20193344

Keywords:

Elective surgery, Hospital stay, Hyperoxygenation, Surgical site infection

Abstract

Background: The aim of this study was to assess the influence of hyperoxygenation on surgical site wound infections.

Methods: Using prospective randomized study, conducted from January 2018 to December 2018 at Mamata Medical College and General hospital, Khammam. This study includes 100 patients who were going for elective surgery at various divisions of Department of surgery. Patients were assigned randomly to an oxygen/air mixture with a faction of inspiration (FiO2) of 30% (n=50) and 60% (n=50). Administration was started after induction of anaesthesia and maintained for 3hours after surgery.

Results: Surgical site infection was recorded in 5 patients (2 of 50, 10%) in the hyperoxygenation group and 11 patients (11 of 50, 22%) in the control group (p<0.05). Time of hospitalization was 5±3 days in the hyperoxygenation group and 9±4 days in the control group (p<0.05).

Conclusions: Hyperoxygenation was associated with a reduction in surgical site infection. It also decreases the duration of hospital stay and decreases economic burden.

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Published

2019-07-25

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Original Research Articles