DOI: http://dx.doi.org/10.18203/2349-2902.isj20192386

A study of clinical presentations and management of cholelithiasis

Sathish Kumar B., Venkat Reddy, Suryanarayana Reddy V., Ram Mohan C., Jahnavi Koneru

Abstract


Background: Cholelithiasis or gallstones, is one of the most common and costly of all the gastrointestinal diseases. Gallstones are associated with high-calorie diets, type 2 diabetes mellitus, dyslipidemia, hyperinsulinism, obesity, and metabolic syndrome. The aim of the study was to analysis the incidence, clinical presentations, and management of cholelithiasis in tertiary care Hospital at Karimnagar, Telangana, India.

Methods: This study was a prospective study; total 50 patients were enrolled in this study. The study was conducted at Department of Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar from September 2016 to September 2017. The data were analyzed and evaluated for clinical profile, management options of cholelithiasis.

Results: The present study shows gallstones diseases are a common problem in female population. The female to male ratio is 3:2. Age, gender and incidence statistically there was no significant in this study.

Conclusions: Gallstones analysis showed mixed stone in 90% of the cases and cholesterol stones in 8% of the cases as the most common variety. The period of post-operative stay in our study was 7 days for open cholecystectomy and 3 days for laparoscopic cholecystectomy in majority of the cases.


Keywords


Cholelithiasis, Gall bladder stone, Outcomes, Ultrasound

Full Text:

PDF

References


Lammert F, Sauerbruch T. Mechanisms of disease: the genetic epidemiology of gallbladder stones. Nat Clin Pract Gastroenterol Hepatol. 2005;2(9):423-33.

Wittenburg H. Hereditary liver disease: gallstones. Best Pract Res Clin Gastroenterol. 2010;24(5):747-56.

Danzinger R, Hofmann AF, Mossa AR. Dissolution of cholesterol gallstones by Chenodeoxycholic acid. New England J Med. 1972;286:1-8.

Roch V, Ksse R, Fromm H, Malavoti. Gallstones dissolution treatment with combination of Chenodeoxycholic acid and ursodeoxycholic acid, Studies on safety, efficacy and effects on high lithogenesity bile acid pool and serum lipids. Digestive Disease Sci. 1986;31:1032-40.

Steven MS, Pierre Alain C. Overview of therapeutic modalities for the treatment of gallstones disease. Am J Surg. 1993;165:420-5.

Hickman MS, Schwesinger WH, Bovia JD, Kurtin WB. Computed tomographic analysis gallstones: An invitro study. Arch Surg. 1986;121:289-91.

Goswitz J T. Bacteria and biliary tract disease. Am J Surg. 1974;128:644.

Bansal A, Murtaza M, Bansal AK. A clinical study: prevalence and management of cholelithiasis. Int Surg J. 2014;1(3):134-9.

Stinton LM, Shaffer EA. Epidemiology of Gallbladder Disease: Cholelithiasis and Cancer. Gut Liver. 2012;6(2):172-87.