A comparative study of vital capacity breath inhalation with sevoflurane versus intravenous propofol to aid laryngeal mask airway insertion in adults

Mahananda Sarkar, Sarbari Swaika, Bikash Bisui, Madhab Chandra Mandal, Swapnadeep Sengupta, Jagabandhu Sheet, Anamitra Mandal


Background: Laryngeal mask airway has already gained widespread acceptance as an alternative airway device and conduit for endotracheal intubation. Insertion of this Supraglottic Airway Device (SAD) to provide and maintain a seal around the laryngeal inlet for spontaneous ventilation as well as modest level of positive pressure ventilation requires a sufficient depth of anaesthesia and depression of airway reflexes to avoid adverse reactions like gagging, coughing, head and limb movements etc. This study was conducted with the intent to compare Vital Capacity Breath (VCB) inhalation with 8% sevoflurane versus intravenous (IV) propofol for quality and ease of insertion of Laryngeal Mask Airway (LMA) and associated complications

Methods: In this prospective, randomized study, 80 adult patients of ASA physical status I and II aged between 20 to 50 years, body weight <70 kg scheduled for short operative procedures under general anaesthesia were selected. The patients were divided into two groups. Group-S (n=40) were induced with 8% sevoflurane with 67% nitrous oxide in oxygen with a total gas flow of 8 litres per minute and group-P (n=40) were induced with injection propofol 2.5 mg/kg body weight intravenously.

Results: Insertion of LMA at first attempt was 92.5% with sevoflurane (VCB) and 95% with propofol. Time to loss of consciousness was 35.98 ± 6.23s and 36.26 ± 5.65s in group S and group P respectively. Complications were similar in both the groups.

Conclusions: A vital capacity induction with sevoflurane shows a slight faster loss of consciousness. The time to successful LMA insertion at 1st attempt and the incidence of side effects were similar in both the group (P >0.05).


Laryngeal mask airway (LMA), Vital capacity breath (VCB), Intravenous (IV), Sevoflurane, Propofol

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