Typhoid fever colitis with massive lower gastrointestinal bleeding

Yousif Salem, Keith Johnston, Amro Salem


Authors are presenting the case of a 34year old female, with no known comorbidities, who after recent travel to Pakistan, presented with fever for 1 month and was diagnosed with typhoid fever.

During her admission she developed bleeding per rectum and abdominal pain labeled as right-side colitis, confirmed by endoscopy and CT scan, which was managed surgically by extended right hemicolectomy and ileostomy.

The aim of this case is to discuss a rare complication of typhoid fever which is lower gastrointestinal bleeding, and high light the importance of considering rare infectious cases if not in endemic areas.


Colitis, Enteric fever, Salmonella typhi, Typhoid

Full Text:



Bhagwan J, Bansal A, Bansal S. Atypical Presentation of typhoid fever: a case report. Available at:

Ezzat RF, Hussein HA, Baban TS, Rashid AT, Abdullah KM. Typhoid ulcer causing life-threatening bleeding from Dieulafoy's lesion of the ileum in a seven-year-old child: a case report. J Med Case Reports. 2010 Dec;4(1):171.

Grimm M, Lübbert C, Mössner J, Weis S. A young traveller presenting with typhoid fever after oral vaccination: a case report. J Med Case Reports. 2013 Dec;7(1):237.

Ayub U, Khattak AA, Saleem A, Javed F, Siddiqui N, Hussain N, et al. Incidence of typhoid fever in Islamabad, Pakistan. Am-Eurasian J Toxicol Sci. 2015;7(4):220-3.

Non LR, Patel R, Esmaeeli A, Despotovic V. Typhoid fever complicated by hemophagocytic lymphohistiocytosis and rhabdomyolysis. Am J Trop Med Hygiene. 2015 Nov 4;93(5):1068-9.

Radhakrishnan A, Als D, Mintz ED, Crump JA, Stanaway J, Breiman RF, Bhutta ZA. Introductory article on global burden and epidemiology of typhoid fever. Am J Trop Med Hygiene. 2018 Sep 6;99(3_Suppl):4-9.

De Mel S, Wong RK. Massive gastrointestinal hemorrhage secondary to typhoid colitis: a case report and literature review. ID Cases. 2015 Jan 1;2(3):83-5.