Association of body mass index, urinary pH and urolithiasis

Authors

  • Surendra Kumar Shrivastava Department of Surgery, Gandhi Medical College, Bhopal, Madhya Pradesh
  • Mool Chand Songra Department of Surgery, Gandhi Medical College, Bhopal, Madhya Pradesh
  • Romil Jain Department of Surgery, Gandhi Medical College, Bhopal, Madhya Pradesh

DOI:

https://doi.org/10.18203/2349-2902.isj20162754

Keywords:

BMI, Urinary stones, Calcium phosphate, Hyperinsulinemia

Abstract

Background:Urinary stones have afflicted mankind since antiquity, with earliest recorded being bladder and kidney stones detected in Egyptian mummies dated 4800 BC. In our study we aimed to determine the association of BMI, urinary pH and urolithiasis.

Methods: The study was conducted in the department of surgery, Gandhi Medical College, Bhopal.  A total of 100 patients who underwent open surgical procedures for urolithiasis were included in the study. The study was carried out from October 2013 to October 2014. The data collected was analyzed for association of BMI with urinary pH, serum creatinine, serum uric acid and serum calcium. Also the effect of body mass index BMI on the chemical composition of stone was studied.

Results:A total of 100 patients of urolithiasis undergoing nephrolithotomy, pyelolithotomy or ureterolithotomy were included in the study. The patients were divided into three groups according to BMI as stated above. The result of inter group comparison showed a statistically significant increase in presence of calcium oxalate and uric acid stones with increasing BMI. The presence of calcium phosphate stone did not indicate any significant change with changing BMI.

Conclusions:Hyperinsulinemia and insulin resistance play an important role in etiology of uric acid stones, hence all patients with uric acid stones should be screened for diabetes.

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Published

2016-12-09

Issue

Section

Original Research Articles