DOI: http://dx.doi.org/10.18203/2349-2902.isj20174887

Clinicopathological study of diabetic foot in Bundelkhand area with special reference to fungal infection in asymptomatic feet of diabetic patients

Mayank Mishra, Dinesh Pratap

Abstract


Background: As with substantial increasing in incidence of diabetes mellitus in present century and with huge prevalence in population; the incidence of one of the dreadful complication of diabetes i.e. diabetic foot also increases, leading to increase morbidity and mortality. Fungal infection in foot is one of the underweighted cause of foot ulceration. These microulceration in conjunction with diabetes may leads to fulminant infection. The study comprised of 66 cases out of which 16 served as control. Aim and objectives of our study is to study the incidence of fungal infection in asymptomatic feet of diabetic patients, identification of the type of fungus, comparison with nondiabetics and clinicopathological study of the patients.

Methods: The present study was carried at Department of Surgery, MLB. Medical College, Jhansi, the study group was classified into two groups. Control group; this group comprised of non-diabetic patients with foot lesions. Disease group; diabetic patients with foot lesions. Webs scrapings were inoculated in Sabouraud’s media slopes. Cultured media were examined after 3 days for the growth. Identification depends on colonial appearance and the morphology of the spores and by Gram, s and AFB Staining.

Results: By this study we conclude that fungal infection in asymptomatic foot of diabetes patient are significantly more than non-diabetic patients which is accentuated by duration, type, glycaemic control and practice of bare foot walking which makes diabetic patient more prone for diabetic foot. So, the foot care of patients of diabetes should include the prophylactic steps to prevent fungal growth.

Conclusions: By above study, we reasonably conclude that fungal infection in diabetic patients plays a pivotal role in formation of diabetic foot disease, so by eradication of fungal infection in asymptomatic foot of diabetic patient by general preventive methods and/or pharmacological methods may be beneficial in reducing morbidity and mortality in diabetic foot patients.


Keywords


Asymptomatic foot, Diabetic foot, Fungal infection

Full Text:

PDF

References


Srivastav A. Sinha R. Clinicopathological study of diabetic foot In Bundelkhand area; 2007. http://archiv.org/stream/in.ernet.../2015.269535

Joshi SR, Parikh RM. India- diabetes capital of the world: now heading towards hypertension. J Assoc Physicians India. 2007;55:323-4.

Greenwood AM, Rockwood EM. The skin in diabetic patients. Archives Dermatol. 1930;21:96-107.

Deplisis DJ. Lesions of the feet in patients with diabetes mellitus. South African J Surg. 1970;8:129.

Catterall RCF. The diabetic foot. Brit J Hosp Med. 1972;7:224.

Bell ET. Atherosclerotic gangrene of the lower extremities in diabetic and nondiabetic persons. Ame J Clin Pathol. 1957;28(1):27-36.

Drachman RH, Root RK, Wood WB. Studies on the effect of experimental non-hepatic diabetes mellitus on antibacterial defence. Demonstration of a Defect in Phagocytosis. J Exp Med. 1966;124:227.

Ainsworth SK, Allison F. Studies on the pathogenesis of acute inflammation. The influence of hyperosmolarity secondary to hyperglycemia upon the acute inflammatory responses induced by thermal injury to ear chamber of rabbits. J Clin Invest. 1970;49:433.

Bagdade JD, Nielson K, Root R, Bulger R. Host defence in diabetes mellitus: the feckless phagocytes during poor control and ketoacidosis. J Diabetes. 1970;1(19):364.

Mckittrick LS. Recent advances in the case of the surgical complication of diabetes mellitus. New Eng J Med. 1946;235:929-32.

Buerger L. The circulatory disturbance of the extremities, Philadelphia, W; B. Saunders; 1924.

Stokes IA, Faris IB, Hutton WC. The neuropathic ulcer and loads on the foot in diabetic patients. Acta Orthopaedica Scandinavica. 1975;46(5):839-47.

Blumenthal H, Joshi R, Goldenberg S, Alex M. Nonatheromatous peripheral vascular disease of the lower extremities in diabetes mellitus. Diabetes. 1959;8:261.

Faris IB. Blood flow in the normal and· diabetic foot. Surg. 1975;45:425.

Bryfogle YW, Bradley RF. Vascular complication of diabetes mellitus. Diabetes. 1957;6:159.

Broughton RB. Reinfection from Socks and Shoes in Tinea pedis. Brit J Derm. 1955;67:24.