DOI: http://dx.doi.org/10.18203/2349-2902.isj20172799

Early gallbladder carcinoma with cholelithiasis: a rare case report

Senthil Kumar A. C., Balamurali S., Reshma S.

Abstract


Gall bladder carcinoma is an exceedingly rare and fatal cancer with a high mortality rate.  Detecting gall bladder carcinoma in early stages can be difficult, despite improvements in ultrasound and computed tomography (CT) imaging. Most diagnoses of gallbladder carcinoma are made at advanced stages, with majority being found incidentally during surgery for cholelithiasis.  The presented case demonstrates suspicion of Gallbladder carcinoma pre-operatively.

 


Keywords


Cholelithiasis, Cholecystectomy, Extended lymphadenectomy, Gallbladder, Gallbladder carcinoma

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References


Shaffer EA. Gallbladder cancer: the basics. Gastroenterol Hepatol (NY). 2008;4(10):737-41.

Duffy A, Capanu M, Abou-Alfa GK. Gallbladder cancer (GBC): 10 - year experience at memorial sloan - kettering cancer centre (MSKCC). J Surg Oncol. 2008;98:485-9.

Carriaga MT, Henson DE. Liver, gallbladder, extrahepatic bile ducts, and pancreas. Cancer. 1995;75:171-90.

Zatonski WA, Lowenfels AB, Boyle P. Epidemiologic aspects of gallbladder cancer: a case - control study of the search program of the International agency for Research on cancer. J Natl Cancer Inst. 1997;891:1132-8.

Rustagi T, Dasanu CA. Risk factors for gallbladder cancer and cholangiocarcinoma: similarities, differences and updates. J Gastrointest Cancer. 2012;43:137-47.

Hsing AW, Gao YT, Han TQ. Gall stones and the risk of biliary tract cancer: a population based study in china. Br J Cancer. 2007;97:1577-82.

Randi G, Malvezzi M, Levi F, Ferlay J, Negri E, Franceschi S, La Vecchia C. Epidemiology of biliary tract cancers: an update. Ann Oncol. 2009;20(1):146-59.

Carriaga MT, Henson DE. Liver, gallbladder, extrahepatic bile ducts, and pancreas. Cancer. 1995;75 (1):171-190.

Groot Koerkamp B, Fong Y. Outcomes in biliary malignancy. J Surg Oncol. 2014;110:585.

Cariati A, Piromalli E, Cetta F. Gallbladder cancers: associated conditions, histological types, prognosis and prevention. Eur J Gastroenterol Hepatol. 2014;26:562-9.

Horgan AM, Amir E, Walter T, Knox JJ. Adjuvant therapy in the treatment of bilairy tract cancer: a systematic review and meta-analysis. J Clin Oncol. 2012;30:1934-40.

Wang SJ, Lemieux A, Kalpathy - Cramer J. Nomogram for predicting the benefit of adjuvant chemoradiotherapy for resected gallbladder cancer. J Clin Oncol. 2011;29:4627-4632.

Misra S, Chaturvedi A, Misra NC, Sharma ID. Carcinoma of the gallbladder. Lancet Oncol. 2003;4:167-76.

Lohe F, Meimarakis G, Schauer C, Angele M, Jauch KW, Schauer RJ. The time of diagnosis impacts surgical management but not the outcome of patients with Gallbladder Carcinoma. Eur J Med Res. 2009;14:345-51.

Strom BL, Maislin G, west SL. Serum CEA and CA 19-9: Potential future diagnostic or screening tests for gallbladder cancer. Int J Cancer. 1990;45:821-4.

Ritts RE, Nagorney DM, Jacobsen DJ, Talbot RW, Zurawski VR. Comparison of preoperative serum CA 19-9 levels with results of diagnostic imaging modalities in patients undergoing laparotomy for suspected pancreatic or gallbladder disease. Pancreas. 1994;9:707-716.

Wibbenmeyer LA, Sharafuddin MJ, Wolverson MK, Heiberg EV, Wade TP, Shields JB. Sonographic diagnosis of unsuspected Gallbladder cancer: imaging findings in comparison with benign Gallbladder conditions. AJR Am J Roentgenol. 1995;165:1169-74.

Kumar A, Aggarwal S. Carcinoma of the gallbaldder: CT findings in 50 cases. Abdom Imaging. 1994;19:304-8.

Ohtani T, shirai Y, Tsukada K, Muto T, Hatakeyama K. Spread of gallbladder carcinoma: CT evaluation with pathologic correlation. Abdom Imaging. 1996;21:195-201.

Schwartz LH, Black J, Fong Y. Gallbladder carcinoma: findings at MR imaging with MR cholangiopancreatography. J Comput Assist Tomogr. 2002;26:405-10.

Sugiyama M, Atomi Y, Yamato T. Gut endoscopic ultrasonography for differential diagnosis of polypoid gallbladder lesions, analysis in surgical and follow up series. 2000;46:250-4.

Sadamoto Y, Kubo H, Harada N, Tanaka M, Eguchi T, Nawata H. Preoperative diagnosis and staging of gallbladder carcinoma by EUS. Gastrointest Endosc. 2003;58:536-41.