Adult intussusception: unusual cause

Senthil Kumar A. C., Malar Vannan M.


Adult intussusception is a rare entity which accounts for 1-5% of intestinal obstructions in adults and just 5% of all cases of intussusception. The basic pathology and management of intussusception in adults differs from paediatric intussusception. Here we present an interesting case of adult intussusception with an unusual cause.  A 33-year-old female presented with features of intestinal obstruction. Colonoscopy was done outside our institution which reported a smooth polypoidal mass in the terminal ileum, biopsy report was pending at that time. CT abdomen revealed dilated small bowel with narrowing in the ileo caecal junction. We proceeded with laparotomy. Intraoperatively dilated ileum with intussusception of the ileocecal junction into the ascending colon was found. Right hemicolectomy with ileotransverse colon anastomosis was done. Histopathology revealed Polyp with intussusception, 5cm from ileocecal junction, with sheets of lymphoid cells showing moderate pleomorphism, infiltrating submucosa, muscularis propria, and serosa, margins uninvolved with lymph node- 3/32 positivity. Immunohistochemistry suggested B- cell lymphoma with CD20 positivity and Bcl 2 focal positivity. Routine treatment of Lymphoma after confirming with biopsy have been Chemotherapy. Role of surgeon in lymphoma is presently limited to biopsy, but there are situations like obstruction and perforation, where surgeon should take the lead role


GIT Lymphoma, Intussusception, Intestinal obstruction, Non- Hodgkin’s lymphoma

Full Text:



Azar T, Berger DL. Adult intussusception. Ann Surg. 1997;226:134-8.

Marinis A, Yiallourou A, Samanides L. Intussusception of the bowel in adults: a review. World J Gastroenterol. 2009;15(4):407-11.

Rocco O. İntussuception in adults. In: Welch JP, ed. Bowel obstruction: differential diagnosis and clinical management. Philadelphia: WB Saunders; 1990.

Taraneh A, Berger BL. Adult intussusception. Ann Surg. 1997;226:134-40.

Begos DG, Sandor A, Modlin IM. The diagnosis and management of adult intussusception. Am J Surg. 1997;173:88-94.

Cooper DL, Daria R, Salloum E. Primary gastrointestinal lymphomas. Gastroenterologist. 1996;4:54-64.

Pandey M, Wadhwa MK, Patel HP. Malignant lymphoma of the gastrointestinal tract. Eur J Surg Oncol. 1999;25:164-7.

Kohno S, Ohshima K, Yoneda S, Kodama T, Shirakusa T, Kikuchi M. Clinicopathological analysis of 143 primary malignant lymphomas in the small and large intestines based on the new WHO classification, Histopathology. 2003;43(2);135-43.

Nagorney DM, Sarr MG, Mcllrath DC. Surgical management of intussusception in the adult. Ann Surg. 1981;193:238

Weilbaecher D, Bolin JA, Hearn D, Ogden W. Intussusception in adults: review of 160 cases. Am J Surg. 1971;121:531-5.

Stubenbord WT, Thorbjarnarson B. Intussusception in adults. Ann Surg. 1970;172:306-10.

Youngson GG. Small bowel lymphoma presenting as chronic adult intussusception. Scott Med J. 1981;26:260-1.

Bazzocchi R, Palmieri V, Lafratta V. Ileo-ceco-colic invagination. A proposal of a case caused by lymphoma of the last ileal loop. Minerva Chir. 1980;15(35):1295-302.