Modified Graham’s repair for peptic ulcer perforation: reassessment study

Authors

  • Bhavinder K. Arora Department of Surgery, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India http://orcid.org/0000-0003-3650-8415
  • Rachit Arora MBBS student final year, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India
  • Akshit Arora MBBS student 2nd year, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India

DOI:

https://doi.org/10.18203/2349-2902.isj20171618

Keywords:

Duodenal perforation, Graham’s patch, Modified Graham’s repair, Pedicled omentoplasty, Peptic perforation

Abstract

Background: Peptic perforation is an emergency and requires urgent surgical treatment. Many modalities of treatment are available ranging from conservative treatment to laparoscopic repair. There is no consensus on treatment of perforated pylorodudenal ulcer which can be treated with conservative treatment, simple closure of ulcer, closure of ulcer with free omentum, closure of perforation with use of pedicled omentum, definitive treatment with truncal vagotomy and drainage procedures or parietal cell vagotomy. However best treatment is still to be decided.

Methods: This study was conducted in department of surgery 60 patients presenting with peptic perforation in last three years. All patients with duodenal perforation in first part (D1) were included in the study. Pyloric perforations, multiple perforations, traumatic perforations and severe co-morbid condition were excluded from study. A pedicled omentum was used in the repair of duodenal perforation. Immediate and late postoperative complications were recorded. The patients were followed for three months.

Results: Out of 60 cases there were 50 male patients and 10 female patients. The majority of male patients were in the middle age group between 35 to 45 years of age and the female patients were of older age group between 40 to 65 years of age. These patients presented with history of acute pain abdomen in the epigastric region. All the patients underwent modified Graham’s patch repair. In postoperative period, two patients had burst abdomen on fourth postoperative day. Biliary fistula formation occurred in 2 patients. Wound infection occurred in 4 patients and the hospital stay was 5 to 9 days. There was no mortality recorded in this series.

Conclusions: In summary, the surgery for perforated peptic ulcer should use modified Graham’s repair using pedicled omentum giving excellent results in terms of healing, morbidity and mortality.

Author Biography

Bhavinder K. Arora, Department of Surgery, Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India

Professor Department of Surgery

Pt B D Sharma PGIMS, Rohtak - 124001

References

Nuhu A, Madziga AG, Gali BM. Acute perforated duodenal ulcer in Maiduguri. Internet J Surg. 2009;21:1.

Windsor JA, Hill AG. The management of perforated peptic ulcer. N Z Med J. 1995;47-8.

Berne TV, Donovan AJ. Nonoperative treatment of perforated duodenal ulcer. Arch Surg. 1989;124(7):830-2.

Testini M, Portincasa P, Piccinni G, Lissidini G, Pellegrini F, Greco L. Significant factors associated with fatal outcome in emergency open surgery for perforated peptic ulcer. World J Gastroenterol. 2003;9:2338-40.

Syanes C, Lie RT, Syanes K, Kie SA, Soreide O. Adverse effects of delayed treatment for perforated peptic ulcer. Ann Surg. 1994;220(2):168-75.

Hill AG. The management of perforated peptic ulcer in a resource poor environment. East Afr Med J. 2001;78(8):346-8.

Budzynski P, Pedziwiatr M, grzesiak-Kuik A, Natkaniec M, Major P, Matlok M, et al. Changing patterns in the surgical treatment of perforated duodenal ulcer- single centre experience. Wideochir Tech Maloinwazyine. 2015;10(3):430-6.

Gutierrez L, Pena C, Merquez R, Fakih F, Adame E, Medina J. Simple closure or vagotomy and pyloroplasty for the treatment of a perforated duodenal ulcer comparison of results. Dig Surg. 2000;17:225.

Nasio NA, Saidi H. Perforated peptic ulcer disease at Kenyatta National Hospital, Nairobi. East Central African J Surg. 2009;14(1):13-6.

Tessema E, Meskel Y, Kotiss B. Perforated peptic ulcer in Tikur Anbessa Hospital. Ethiop Med J. 2005;43(1):9-13.26.

Graham RR. Treatment of perforated duodenal ulcers. Surg Gynecol Obstet. 1937;64:235-8.

Satapathy MC, Dash D, Panda C. Modified Grahams’ omentopexy in acute perforation of first part of duodenum; A tertiary level experience in south India. Saudi Surg J. 2013;1:33-6.

Shah FH, Mehta SG, Gandhi MD, Saraj. Laparoscopic peptic ulcer perforation closure: the preferred choice. Ind J Surg. 2015;77(2):403-6.

Bertleff MJOE, Stegmann T, Liem RSB, Kors G, Robinson PH, Nicoai JP. Comparison of closure of gastric perforation ulcers with biodegradable Lactide-Glycolide-Caprolactone or Omental Patches. JSLS. 2009;13:550-4.

Bertleff MJOE, Lange JF. Perforated peptic ulcer disease: A review of history and treatment. Dig Surg. 2010;27:161-9.

Arveen S, Jagdish S, Kadambari D. Perforated peptic ulcer in South India: An Institutional perspective. World J Surg. 2009;33:1600-4.

Rajput IA, Iqbal M, Manzar S. Comparison of omentopexy techniques for duodenal perforation. Pak J Surg. 2000;16:1-6.

Hermansson M, Holstein CS, Zilling T. Surgical approach and prognostic factors after peptic ulcer perforation. Eur J Surg. 1999;165:566-72.

Kumar K, Pai D, Srinivasan K, Jagdish S, Ananthakrishnan N. Factors contributing to releak after surgical closure of perforated duodenal ulcer by Graham’s Patch. Trop Gastroenterol. 2002;23:190-2.

Sebastian M, Chandran VP, Elashaal YI, Sim AJ. Heliobacter pylori infection in perforated peptic ulcer disease. Br J Surg. 1995;82:360-2.

Fallat ME, White MJ, Richardson JD, Flint LM. Reassessment of Graham-Steele closure in acute perforated peptic ulcer. South Med J. 1983;76(10):1224-4.

Tsugawa K, Koyanagi N, Hashizume M, Tomikawa M, Akahoshi K, Ayukawa K, et al. The therapeutic strategies in performing emergency surgery for gastroduodenal ulcer perforation in 130 patients over 70 years of age. Hepatogastroenterology. 2001;48(37):156-62.

Wong CW, Chung PH, Tam PK, Wong KK. Laparoscopic versus open operation for perforated peptic ulcer in pediatric patients: A 10-year experience. J Pediatr Surg. 2015;50(12):2038-40.

Chernookov AI, Naumov BA, Kotaev A, Belykh EN, Ramishvili V, Timoshin NN. Surgical treatment of patients with perforated peptic ulcers. Khirugiia (Mosk). 2007;6:34-9.

Kocer B, Surmeli S, Solak C, Unal B, Bozkurt B, Yildrim O, et al. Factors affecting mortality and morbidity in patients with peptic ulcer perforation. J Gastroenterol Hepatol. 2001;22:565-70.

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Published

2017-04-22

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Original Research Articles